Craving carbs? Blame an ancient gene.

We, Neanderthals, and Denisovans all have extra copies of a starch-digesting enzyme.

Dec 27, 2024 - 12:59
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Craving carbs? Blame an ancient gene.

There is now a genetic excuse not to bother cutting carbs. Humans have genetically adapted to eating starchy foods, and our ancestors may have been carb-ivores even before modern Homo sapiens emerged.

The salivary amylase gene, known as AMY1, is already known to have helped us adapt to eating carbs. It encodes amylase, an enzyme that breaks starches found in pasta and bread down to glucose—and may have given us a taste preference for them. Humans have multiple copies of the gene, which may help us produce high levels of the enzyme.

Researchers from the University of Buffalo and the Jackson Laboratory have now found that, while most copies of this gene arose with the advent of farming, modern humans and our closest relatives had accumulated extra copies long before agriculture.

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